The Cellular Cost of Standard Care | The Negative Side-Effects of Commonly Prescribed Medication

Course overview

What you will study

This educational activity examines the metabolic and cellular consequences of three widely prescribed drug classes: statins, metformin, and proton pump inhibitors. It explores how these interventions can deplete cellular substrates, disrupt mitochondrial function, and impair downstream physiology, while presenting evidence-based support protocols and therapeutic alternatives.

Learning objectives

Key learnings

• Differentiate the pathogenesis and salutogenesis clinical frameworks and apply the Health Optimization Medicine model to identify medication-induced cellular deficits in patient care.
• Identify downstream metabolic consequences of HMG-CoA reductase inhibition, including CoQ10 depletion, impaired steroidogenesis, and disrupted protein prenylation.
• Evaluate mitochondrial and nutritional costs of metformin therapy, including ATP depletion and Vitamin B12 malabsorption.

Your faculty

J.P. Kuipers, MD

Credit and completion

Enduring post-test with 80% score and evaluation required.

After checkout, your Academy access instructions arrive by email. Complete the course requirements to receive any applicable certificate and CME claim guidance.