Killing ourselves by Forgetting the Brakes | A Deep Dive into GABA, Positive Allosteric Modulators, and Natural Equivalents

Course overview

What you will study

This educational activity provides a comprehensive review of GABA physiology, its role as the primary inhibitory neurotransmitter, and its clinical relevance in mental health and systemic conditions. It covers GABA deficiency, receptor subtypes, medication risks, positive allosteric modulation, obligate pairing, and lifestyle/nutritional interventions.

Learning objectives

Key learnings

• Identify clinical presentations and symptom patterns associated with GABA deficiency.
• Differentiate GABA-A and GABA-B receptor mechanisms.
• Evaluate risks and limitations of commonly used GABAergic medications.
• Incorporate metabolic, nutritional, and lifestyle-based strategies to optimize endogenous GABA production.
• Develop individualized treatment plans using evidence-based approaches including positive allosteric modulation and integrative therapies.

Your faculty

Dr. Scott Sherr, MD

Credit and completion

Enduring post-test with 80% score and evaluation required.

After checkout, your Academy access instructions arrive by email. Complete the course requirements to receive any applicable certificate and CME claim guidance.