Methylene Blue: The Original Magic Bullet

Course overview

What you will study

This course explores the clinical applications of methylene blue as a versatile, mitochondria-targeted therapeutic agent. It reviews historical use, mechanisms of action as an electron cycler in the mitochondrial electron transport chain, dose-dependent hormetic effects, and clinical relevance for inflammation, oxidative stress, neurodegeneration, infection, and cognitive performance.

Learning objectives

Key learnings

• Apply mitochondrial redox principles to identify clinical scenarios where methylene blue may support cellular energy production and resilience.
• Differentiate low-dose versus higher-dose methylene blue strategies to optimize benefit while minimizing risk.
• Integrate methylene blue into treatment plans for inflammatory, neurocognitive, ischemic, or post-infectious conditions.
• Evaluate patient safety considerations, contraindications, and product quality requirements.

Your faculty

Dr. Scott Sherr, MD

Credit and completion

Post-course quiz required.

After course checkout, your Academy access instructions arrive by email. Your certificate is awarded once you fulfill the course requirements.