Genes are not our destiny. Epigenetics is the study of heritable changes in gene expression and cellular phenotype that do not involve alterations in the underlying DNA sequence. It encompasses a complex interplay between genetic factors and environmental influences, including DNA methylation, histone modifications, non-coding RNA molecules, and chromatin remodeling.
This module was created by renowned researcher and Stanford teacher, Lucia Aronica, Ph.D. and clinically rendered by Dr. Scot Sherr from the HOMeHOPe faculty. It dives deep into the clinical applications of these epigenetic modifications, discusses the potential and pitfalls of epigenetic aging clocks, discusses the profound effect exercise and diet have on epigenetics,and much more.
Required for Essential HOMe/HOPe Course completion. The enrollment prerequisite is the "Certificate of Module Completion in Clinical Metabolomics."
Week 1 - Introduction to the Epigenetics Module
This lesson provides the outline for studying the Epigenetics Module.
Week 2- Epigenetics: A Molecular Framework for HOMe/HOPe
This lesson provides: The HOMe/HOPe perspective, Definitions. Basic Mechanisms, and Implications in Human Health.
Week 3 - DNA Methylation
This lesson focuses on DNA Methylation as one of the 3 main types of epigenetic modification.
Week 4 - Correction of Methylation Imbalances
This lesson lists strategies for correcting methylation imbalances.
Week 5 - Epigenetic Modifications: Histones and Non-Coding RNA
This lesson elucidates the two other main mechanisms for epigenetic modification, aside from DNA methylation which has been discussed in an earlier lesson.
Week 6 - Epigenomic Effects of Diet, Aging, and Lifestyle
This lesson demonstrates the effects of diet, aging, and lifestyle on the epigenome. It includes a discussion of epigenetic clocks and aging.
Week 7 - Epigenetics Module Final Assessment
This is the final examination of the Epigenetics Module. You have 1 week with 2 chances to pass it. If you pass it, you will be awarded your "Certificate of Completion of the Epigenetics Module of the Basic HOMe/HOPe Course." If you don't you will have to re-enroll in the module.
